diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 2ada97551aacc..23f28f98be623 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -21000,9 +21000,14 @@ namespace ts {
          * with no call or construct signatures.
          */
         function isObjectTypeWithInferableIndex(type: Type): boolean {
-            return type.flags & TypeFlags.Intersection ? every((type as IntersectionType).types, isObjectTypeWithInferableIndex) :
-                !!(type.symbol && (type.symbol.flags & (SymbolFlags.ObjectLiteral | SymbolFlags.TypeLiteral | SymbolFlags.Enum | SymbolFlags.ValueModule)) !== 0 &&
-                !typeHasCallOrConstructSignatures(type)) || !!(getObjectFlags(type) & ObjectFlags.ReverseMapped && isObjectTypeWithInferableIndex((type as ReverseMappedType).source));
+            return type.flags & TypeFlags.Intersection
+                ? every((type as IntersectionType).types, isObjectTypeWithInferableIndex)
+                : !!(
+                    type.symbol
+                    && (type.symbol.flags & (SymbolFlags.ObjectLiteral | SymbolFlags.TypeLiteral | SymbolFlags.Enum | SymbolFlags.ValueModule)) !== 0
+                    && !(type.symbol.flags & SymbolFlags.Class)
+                    && !typeHasCallOrConstructSignatures(type)
+                ) || !!(getObjectFlags(type) & ObjectFlags.ReverseMapped && isObjectTypeWithInferableIndex((type as ReverseMappedType).source));
         }
 
         function createSymbolWithType(source: Symbol, type: Type | undefined) {
diff --git a/tests/baselines/reference/mergedClassNamespaceRecordCast.errors.txt b/tests/baselines/reference/mergedClassNamespaceRecordCast.errors.txt
new file mode 100644
index 0000000000000..7c170f7e7cc33
--- /dev/null
+++ b/tests/baselines/reference/mergedClassNamespaceRecordCast.errors.txt
@@ -0,0 +1,34 @@
+tests/cases/compiler/mergedClassNamespaceRecordCast.ts(3,1): error TS2352: Conversion of type 'C1' to type 'Record<string, unknown>' may be a mistake because neither type sufficiently overlaps with the other. If this was intentional, convert the expression to 'unknown' first.
+  Index signature for type 'string' is missing in type 'C1'.
+tests/cases/compiler/mergedClassNamespaceRecordCast.ts(9,1): error TS2352: Conversion of type 'C2' to type 'Record<string, unknown>' may be a mistake because neither type sufficiently overlaps with the other. If this was intentional, convert the expression to 'unknown' first.
+  Index signature for type 'string' is missing in type 'C2'.
+tests/cases/compiler/mergedClassNamespaceRecordCast.ts(12,10): error TS2339: Property 'unrelated' does not exist on type 'C2'.
+
+
+==== tests/cases/compiler/mergedClassNamespaceRecordCast.ts (3 errors) ====
+    class C1 { foo() {} }
+    
+    new C1() as Record<string, unknown>;
+    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+!!! error TS2352: Conversion of type 'C1' to type 'Record<string, unknown>' may be a mistake because neither type sufficiently overlaps with the other. If this was intentional, convert the expression to 'unknown' first.
+!!! error TS2352:   Index signature for type 'string' is missing in type 'C1'.
+    
+    
+    class C2 { foo() {} }
+    namespace C2 { export const unrelated = 3; }
+    
+    new C2() as Record<string, unknown>;
+    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
+!!! error TS2352: Conversion of type 'C2' to type 'Record<string, unknown>' may be a mistake because neither type sufficiently overlaps with the other. If this was intentional, convert the expression to 'unknown' first.
+!!! error TS2352:   Index signature for type 'string' is missing in type 'C2'.
+    
+    C2.unrelated
+    new C2().unrelated
+             ~~~~~~~~~
+!!! error TS2339: Property 'unrelated' does not exist on type 'C2'.
+    
+    
+    namespace C3 { export const unrelated = 3; }
+    
+    C3 as Record<string, unknown>;
+    
\ No newline at end of file
diff --git a/tests/baselines/reference/mergedClassNamespaceRecordCast.js b/tests/baselines/reference/mergedClassNamespaceRecordCast.js
new file mode 100644
index 0000000000000..848f01d70cfbb
--- /dev/null
+++ b/tests/baselines/reference/mergedClassNamespaceRecordCast.js
@@ -0,0 +1,45 @@
+//// [mergedClassNamespaceRecordCast.ts]
+class C1 { foo() {} }
+
+new C1() as Record<string, unknown>;
+
+
+class C2 { foo() {} }
+namespace C2 { export const unrelated = 3; }
+
+new C2() as Record<string, unknown>;
+
+C2.unrelated
+new C2().unrelated
+
+
+namespace C3 { export const unrelated = 3; }
+
+C3 as Record<string, unknown>;
+
+
+//// [mergedClassNamespaceRecordCast.js]
+var C1 = /** @class */ (function () {
+    function C1() {
+    }
+    C1.prototype.foo = function () { };
+    return C1;
+}());
+new C1();
+var C2 = /** @class */ (function () {
+    function C2() {
+    }
+    C2.prototype.foo = function () { };
+    return C2;
+}());
+(function (C2) {
+    C2.unrelated = 3;
+})(C2 || (C2 = {}));
+new C2();
+C2.unrelated;
+new C2().unrelated;
+var C3;
+(function (C3) {
+    C3.unrelated = 3;
+})(C3 || (C3 = {}));
+C3;
diff --git a/tests/baselines/reference/mergedClassNamespaceRecordCast.symbols b/tests/baselines/reference/mergedClassNamespaceRecordCast.symbols
new file mode 100644
index 0000000000000..71f6d7c79a54e
--- /dev/null
+++ b/tests/baselines/reference/mergedClassNamespaceRecordCast.symbols
@@ -0,0 +1,39 @@
+=== tests/cases/compiler/mergedClassNamespaceRecordCast.ts ===
+class C1 { foo() {} }
+>C1 : Symbol(C1, Decl(mergedClassNamespaceRecordCast.ts, 0, 0))
+>foo : Symbol(C1.foo, Decl(mergedClassNamespaceRecordCast.ts, 0, 10))
+
+new C1() as Record<string, unknown>;
+>C1 : Symbol(C1, Decl(mergedClassNamespaceRecordCast.ts, 0, 0))
+>Record : Symbol(Record, Decl(lib.es5.d.ts, --, --))
+
+
+class C2 { foo() {} }
+>C2 : Symbol(C2, Decl(mergedClassNamespaceRecordCast.ts, 2, 36), Decl(mergedClassNamespaceRecordCast.ts, 5, 21))
+>foo : Symbol(C2.foo, Decl(mergedClassNamespaceRecordCast.ts, 5, 10))
+
+namespace C2 { export const unrelated = 3; }
+>C2 : Symbol(C2, Decl(mergedClassNamespaceRecordCast.ts, 2, 36), Decl(mergedClassNamespaceRecordCast.ts, 5, 21))
+>unrelated : Symbol(unrelated, Decl(mergedClassNamespaceRecordCast.ts, 6, 27))
+
+new C2() as Record<string, unknown>;
+>C2 : Symbol(C2, Decl(mergedClassNamespaceRecordCast.ts, 2, 36), Decl(mergedClassNamespaceRecordCast.ts, 5, 21))
+>Record : Symbol(Record, Decl(lib.es5.d.ts, --, --))
+
+C2.unrelated
+>C2.unrelated : Symbol(C2.unrelated, Decl(mergedClassNamespaceRecordCast.ts, 6, 27))
+>C2 : Symbol(C2, Decl(mergedClassNamespaceRecordCast.ts, 2, 36), Decl(mergedClassNamespaceRecordCast.ts, 5, 21))
+>unrelated : Symbol(C2.unrelated, Decl(mergedClassNamespaceRecordCast.ts, 6, 27))
+
+new C2().unrelated
+>C2 : Symbol(C2, Decl(mergedClassNamespaceRecordCast.ts, 2, 36), Decl(mergedClassNamespaceRecordCast.ts, 5, 21))
+
+
+namespace C3 { export const unrelated = 3; }
+>C3 : Symbol(C3, Decl(mergedClassNamespaceRecordCast.ts, 11, 18))
+>unrelated : Symbol(unrelated, Decl(mergedClassNamespaceRecordCast.ts, 14, 27))
+
+C3 as Record<string, unknown>;
+>C3 : Symbol(C3, Decl(mergedClassNamespaceRecordCast.ts, 11, 18))
+>Record : Symbol(Record, Decl(lib.es5.d.ts, --, --))
+
diff --git a/tests/baselines/reference/mergedClassNamespaceRecordCast.types b/tests/baselines/reference/mergedClassNamespaceRecordCast.types
new file mode 100644
index 0000000000000..8d15fe5151291
--- /dev/null
+++ b/tests/baselines/reference/mergedClassNamespaceRecordCast.types
@@ -0,0 +1,46 @@
+=== tests/cases/compiler/mergedClassNamespaceRecordCast.ts ===
+class C1 { foo() {} }
+>C1 : C1
+>foo : () => void
+
+new C1() as Record<string, unknown>;
+>new C1() as Record<string, unknown> : Record<string, unknown>
+>new C1() : C1
+>C1 : typeof C1
+
+
+class C2 { foo() {} }
+>C2 : C2
+>foo : () => void
+
+namespace C2 { export const unrelated = 3; }
+>C2 : typeof C2
+>unrelated : 3
+>3 : 3
+
+new C2() as Record<string, unknown>;
+>new C2() as Record<string, unknown> : Record<string, unknown>
+>new C2() : C2
+>C2 : typeof C2
+
+C2.unrelated
+>C2.unrelated : 3
+>C2 : typeof C2
+>unrelated : 3
+
+new C2().unrelated
+>new C2().unrelated : any
+>new C2() : C2
+>C2 : typeof C2
+>unrelated : any
+
+
+namespace C3 { export const unrelated = 3; }
+>C3 : typeof C3
+>unrelated : 3
+>3 : 3
+
+C3 as Record<string, unknown>;
+>C3 as Record<string, unknown> : Record<string, unknown>
+>C3 : typeof C3
+
diff --git a/tests/cases/compiler/mergedClassNamespaceRecordCast.ts b/tests/cases/compiler/mergedClassNamespaceRecordCast.ts
new file mode 100644
index 0000000000000..830cbc4e4858b
--- /dev/null
+++ b/tests/cases/compiler/mergedClassNamespaceRecordCast.ts
@@ -0,0 +1,17 @@
+class C1 { foo() {} }
+
+new C1() as Record<string, unknown>;
+
+
+class C2 { foo() {} }
+namespace C2 { export const unrelated = 3; }
+
+new C2() as Record<string, unknown>;
+
+C2.unrelated
+new C2().unrelated
+
+
+namespace C3 { export const unrelated = 3; }
+
+C3 as Record<string, unknown>;