diff --git a/src/extended_json.ts b/src/extended_json.ts
index b7bb1b03..90269623 100644
--- a/src/extended_json.ts
+++ b/src/extended_json.ts
@@ -285,7 +285,17 @@ function serializeDocument(doc: any, options: EJSONSerializeOptions) {
     for (const name in doc) {
       options.seenObjects.push({ propertyName: name, obj: null });
       try {
-        _doc[name] = serializeValue(doc[name], options);
+        const value = serializeValue(doc[name], options);
+        if (name === '__proto__') {
+          Object.defineProperty(_doc, name, {
+            value,
+            writable: true,
+            enumerable: true,
+            configurable: true
+          });
+        } else {
+          _doc[name] = value;
+        }
       } finally {
         options.seenObjects.pop();
       }
diff --git a/test/node/bson_test.js b/test/node/bson_test.js
index 484d9c07..ac178000 100644
--- a/test/node/bson_test.js
+++ b/test/node/bson_test.js
@@ -1776,7 +1776,12 @@ describe('BSON', function () {
     assertBuffersEqual(done, serialized_data, serialized_data2, 0);
 
     var doc1 = BSON.deserialize(serialized_data);
-    expect(Object.getOwnPropertyDescriptor(doc1, '__proto__').enumerable).to.equal(true);
+    expect(doc1).to.have.deep.ownPropertyDescriptor('__proto__', {
+      configurable: true,
+      enumerable: true,
+      writable: true,
+      value: { a: 42 }
+    });
     expect(doc1.__proto__.a).to.equal(42);
     done();
   });
diff --git a/test/node/extended_json_tests.js b/test/node/extended_json_tests.js
index f3e6cea8..e8f97457 100644
--- a/test/node/extended_json_tests.js
+++ b/test/node/extended_json_tests.js
@@ -509,6 +509,20 @@ describe('Extended JSON', function () {
     // expect(() => EJSON.serialize(badMap)).to.throw(); // uncomment when EJSON supports ES6 Map
   });
 
+  it('should correctly deserialize objects containing __proto__ keys', function () {
+    const original = { ['__proto__']: { a: 42 } };
+    const serialized = EJSON.stringify(original);
+    expect(serialized).to.equal('{"__proto__":{"a":42}}');
+    const deserialized = EJSON.parse(serialized);
+    expect(deserialized).to.have.deep.ownPropertyDescriptor('__proto__', {
+      configurable: true,
+      enumerable: true,
+      writable: true,
+      value: { a: 42 }
+    });
+    expect(deserialized.__proto__.a).to.equal(42);
+  });
+
   context('circular references', () => {
     it('should throw a helpful error message for input with circular references', function () {
       const obj = {